The FlexHD Pliable PRE, an internal dermal brassiere, was created by Aldona Spiegel, M.D., and inspired by her sewing experience.

Spiegel created the internal dermal brassiere from acellular dermal matrix that would support and hold the implant while allowing its installation in the same space where the breast tissue was removed from. This creates a more natural reconstruction without deforming the muscle or pulling the skin.