Microneedling or subcision combined with platelet-rich plasma (PRP) is more effective than microneedling or subcision alone for reducing the severity of atrophic acne scars, according to study research published in the Journal of Cosmetic Dermatology.

The study findings were derived from a meta-analysis of 8 trials that compared microneedling or subcision with PRP vs microneedling or subcision without PRP in patients with atrophic acne scars (N=311). Trials included whole-face participants (n=153) and split-face participants (n=158). Across the 8 trials, 238 participants were treated with a combination therapy plus adjunct PRP and 239 participants were treated with a single therapy that did not use PRP.