A study published in Cell by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Centro Nacional de Análisis Genómico of the Center for Genomic Regulation (CNAG-CRG) explains how dermal fibroblasts age.
The main conclusion drawn is that these fibroblasts lose their cell identity, as if they had “forgotten” what they are, and consequently their activity is altered, thus affecting tissue. The study reveals the cellular and molecular pathways affected by ageing and proposes that they could be manipulated to delay or even reverse the skin ageing process.
